Photobiomodulation of the gut microbiota: A promising strategy in the treatment and prevention of neuroinflammation

The modern lifestyle, which includes increased stress, unhealthy diet, lack of exercise, and exposure to harmful environmental factors, can disrupt the balance of the gut microbiota (dysbiosis). This condition is associated not only with digestive issues but also with the development of neuroinflammatory processes underlying many neurological and psychiatric disorders.

Photobiomodulation therapy (PBM) offers an innovative approach to restoring and maintaining gut microbiota balance and subsequently alleviating neuroinflammation. A significant scientific review published in the journal Lasers in Medical Science (2025) highlights the ability of low-level laser therapy (LLLT) to positively influence the composition of the gut microbiota, leading to reduced systemic inflammation and support of a healthy gut-brain axis.

Mechanisms of PBM action include:

1. Reduction of inflammatory processes: PBM lowers levels of pro-inflammatory cytokines and increases the production of anti-inflammatory substances, helping to restore immune system balance.

2. Strengthening gut barrier integrity: The therapy helps reinforce the gut barrier, preventing harmful substances from entering the body (“leaky gut” syndrome).

3. Supporting a healthy microbiota: PBM stimulates the growth of beneficial bacterial species and limits unwanted pathogenic bacteria.

Clinical studies and experimental research have shown that PBM is an effective method not only for treatment but also for the prevention of neuroinflammatory diseases such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis.

Special PBM panels from redlight.doctor utilize a unique combination of wavelengths (UVB, UVA, red, and near-infrared spectrum - NIR) optimally designed for maximum therapeutic effect. These panels represent a practical and effective method for preventing and supporting the treatment of many lifestyle-related diseases caused by modern living.

Regular use of these special PBM panels can help:

• Maintain optimal gut microbiota balance

• Reduce the risk of chronic inflammation

• Improve overall physical and mental health

Using PBM therapy in combination with a healthy lifestyle offers an effective way to minimize the negative impacts of modern life on our health. For more information, you can read the full review article here: Lasers in Medical Science, 2025 (https://link.springer.com/article/10.1007/s10103-025-04319-9).