Light, Gut, and Brain: A Comprehensive View of Overweight

Being overweight is often seen as a simple result of excessive calorie intake and lack of physical activity. However, current research suggests that it is much more complex and may start where we least expect it – in our eyes and gut microbiota.

We start with the eyes. Research shows that a changed - unnatural light spectrum can affect our retina and thus the brain. This effect is manifested in the regulation of body weight, where disturbed light conditions can lead to an imbalance.

Next, let's look at the intestinal microflora. Suboptimal bacteria produce lipopolysaccharides (LPS), which are toxins that can increase leptin levels in the blood. Leptin is a hormone that regulates satiety. When its level is high for a long time, it can lead to leptin resistance. This condition disrupts the proper functioning of the body in response to this hormone, which can contribute to the development of obesity.

Leptin resistance further affects the brain. It causes disruption of DHA recycling in the retina and slowing down of circadian rhythms. These changes affect eating behavior, including a decrease in dopamine levels in the brain, which affects our appetites and feelings of satiety.

Increased intestinal LPS can lead to the development of cerebral cavernous malformations (CCMs), which are clumps of blood vessels in the brain. These malformations can lead to serious health problems such as seizures or strokes.

Research has also pointed to the importance of the light environment and its influence on processes in the body. It turns out that our exposure to light can have a significant impact on our health, including the development of obesity.

In connection with our approach to weight loss and a healthy lifestyle, it is necessary to realize the key importance of light, which plays a significant role not only in relation to excess weight, but also to overall health. Modern artificial lighting, especially blue light from electronic devices, has the potential to disrupt our circadian rhythms and hormonal balance. The effect of isolated blue light on the peptide POMC (proopiomelanocortin), ACTH (adrenocorticotropic hormone) and CLIP deserves special attention. This light can 'hijack' these hormones, leading to increased insulin and blood glucose levels, regardless of what you eat, which is a significant risk factor for obesity and other metabolic problems. Natural sunlight, on the other hand, plays a vital role in regulating sleep, mood and metabolic processes, and exposure to natural light can help regulate important hormones such as leptin, which is key to proper weight management. This aspect highlights how our environment, including exposure to light, can affect our overall health and well-being. Understanding the effect of light on our bodies offers another important tool in the fight against excess weight, pointing to the need to focus not only on diet and exercise, but also on the overall lifestyle and environment in which we live. For this reason, choosing a suitable environment for exercise, especially with regard to lighting, is key. Exercising under artificial light, especially under intense blue light from LED and fluorescent sources, can negatively affect the production of melatonin, important for quality sleep and body regeneration, and can contribute to leptin resistance. In contrast, exercising in natural light, such as outdoors, can support healthy rhythms of leptin and POMC production, help improve body weight regulation, and promote optimal metabolism. Choosing an appropriate exercise environment that respects natural light conditions is therefore key to promoting optimal health and vitality.

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